Topic: Glycoproteins, glycosylation & Cancer This week you learned about carbohydrates and the importance of glycolipids, glycoproteins, and glycosylation for the functional interaction between the different components found in the extracellular matrix (ECM). You further heard about the importance of the proper sequence of the carbohydrates on glycoproteins (the “sugar code”) and the key role […]
Discuss the issues arising in the use of this technology for the routine quantitative measurement of serum protein hormones in the clinical laboratory.
Proteomics for protein hormone measurement Formative and summative assessmentLiquid chromatography mass spectrometry has become the gold standard for analytical measurements of small molecules such as steroid hormones. In recent years, this methodology has become widely used for quantitative analysis of serum steroid hormones in a clinical laboratory setting. However, measurement of protein has been problematic. […]
Glycosylation of protein is an important post-translation modification that plays essential role in biology. Discuss why and how it’s important.
Site-specific glycan analysis of the SARS-CoV-2 spike BY Yasunori Watanabe1,2,3*, Joel D. Allen1*, Daniel Wrapp4 , Jason S. McLellan4 , Max Crispin1 1.Glycosylation of protein is an important post-translation modification that plays essential role in biology. Discuss why and how it’s important. 2.Discuss the glycosylation article in the context of SARS-COV-2 infection. 3.Explain any confusion […]