Darren

Using the scenario below draw the pedigree for this family. What could explain why Darren is unaffected but two of his children are affected?

Module 5 Donna and Darren have three children [2 male/1 female]. Darren’s father has hypercholesterolemia, which is transmitted in an autosomal dominant pattern. Darren gets his cholesterol levels checked frequently, and they have remained within normal limits; however, two of Donna and Darren’s three children have high plasma levels of total and LDL cholesterol. Darren […]

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