(a) Do you think MBB1 can form disulphide bonds. Explain your answer. (3 marks, 3 lines) (b) Which residues of MBB1 could be post-translationally modified? In your answer, state the residues and the post-translational modifications. (4 marks, 4 lines) (c) At physiological pH, what do you think the overall charge of MBB1 will be? Assume […]
How the structural properties of the nanopores influence their functional properties in drug delivery and small molecule sensing applications?.
SECTION C DNA nanopores are synthetic analogues of biological transmembrane protein pores, whichhave been designed for applications in single-molecule sensing and drug delivery. The behaviour of novel DNA nanostructures in the presence of lipid membranes is difficult to predict due to their high charge density and the flexibility of DNA. Describe a protocol for simulating […]
Briefly outline the synthetic strategies available for production of single enantiomer drug products.
Question 1: (500 words) What do you understand by the term ‘heterocyclic compound’? Question 2: (500 words) Clearly distinguish between the following compounds, i) pyrrole ii) furan iii) thiophene iv) Imidazole Question 3: (500 words) Discuss and critically evaluate the theory and applications of the following protein assays -A280nm -Coomassie -Lowry -BCA Question 4: (300 […]
Explain how a chemistry topic you learned in this course can be used to understand the chemistry behind this article.
Use topic of biochemistry In this final post, you will be applying what you have learned in the class to the real world. Choose an article involving chemistry published within the last six months. Explain how a chemistry topic you learned in this course can be used to understand the chemistry behind this article. Be […]
Effects of the C-chain length on the chemical shift and wavenumber.
IB IA’s have very specific grading criteria and outlines that are different from normal High school research papers. My research question is on the effect of the C-chain length on the chemical shift and wavenumber. The writer would need to use databases etc to look into this research question and answer it according to the […]
What was the cause of some batteries bursting into flame? Do you know these rechargeable batteries only have a limited life cycle typically lasting for only 2 to 3 years?
The guideline is in additional material area. MY TOPIC: There have been plenty of news on cell phone batteries recently. What was the cause of some batteries bursting into flame? Do you know these rechargeable batteries only have a limited life cycle typically lasting for only 2 to 3 years? These are some thoughts (you […]
Taking into account the physicochemical characteristics of these active ingredients, propose and justify a formulation, a choice of excipients, a method of manufacture, and control procedures for this drug.
Case study: Oral form with accelerated bioavailability of paracetamol and aspirin A Pharmaceutical company wants to develop and manufacture an oral form with accelerated bioavailability containing paracetamol (300 mg) and aspirin (200 mg). Taking into account the physicochemical characteristics of these active ingredients, propose and justify a formulation, a choice of excipients, a method of […]