A second mutant (designated grn1B) was also found to make a truncated Grn1 protein with the C-terminal sequence below. The mutation was the result of a frameshift mutation and had the C-terminal sequence as follows:
134
N….Ala-Pro-His-Trp-Val….C
Q4) Is the frameshift mutation a +1 or a -1 frameshift mutation? What base was
added/deleted and at which position?
Q5) Describe which methods you could employ to confirm your predictions in (Q1-4)
Q6) Compare and contrast the organisation of the nuclear and mitochondrial genomes. (Max 800 word essay)
Compare and contrast the organisation of the nuclear and mitochondrial genomes.
