Methotrexate in juvenile idiopathic arthritis
Coronavirus is a virus-related group that causes diseases in mammals and its treatment using ivermectin has been a topic in many discussion boards. The impact of coronavirus can not only be mild respiratory tract infection but lethal to human beings. COVID-19 is an infection that results from a severe acute respiratory syndrome coronavirus 2 strain abbreviated as (SARS-CoV-2) (1).
Ivermectin is an anti-parasitic and one of the drugs that can be used to treat the disease. The immunomodulatory properties of Ivermectin are mediated via the cholinergic anti-inflammatory pathway. This can alleviate clinical deterioration, reduce respiratory inflammation (2).
This essay will review the structure of Ivermectin, discuss the molecular target of the drug, highlight the main mechanism of action and the pharmacokinetics parameters. As well as the adverse events of the drug, its pathophysiology and a rationale for generating Ivermectin prescription.
