What is the hypothesis being tested?
What is the disease or health outcome that is being studied?
How is the disease or health outcome assessed?
What is the exposure of primary interest in this study?
How is exposure measured in this study?
What do the authors say the study design is?
What do you say the study design is?
List the details of the methodology that support your answer to question 3.
Explain any reasons why this study design would or would not be appropriate to address this research question.
How does this study design compare to other designs that might be used to address this research question?
List all inclusion and exclusion criteria for study subjects. [HINT: include each in only 1 list – i.e. if you put “age 20-25” in the inclusion list don’t repeat it as “not age 20-25” in the exclusion list. [HINT: if they used matching list the variables matched on]
What is the target population?
How were the study subjects identified or located?
How were subjects invited to participate in the study?
What measures of association and indicators of statistical significance do the authors present? Choose all that apply.
Select ONE potential source of bias in this study.
How does the bias you selected in question 15 operate in this study?
Identify cells in the 2×2 that will have more people in them than they should because of the bias you selected in question 15. [If the bias could cause different cells to increase under different scenarios, choose each of them.]
Identify cells in the 2×2 that will have fewer people in them than they should because of the bias you selected in question 15. Choose all that apply. [If the bias could cause different cells to decrease under different scenarios, choose each of them.]
How will the bias named in question 15 affect the measure of association (the relative risk or odds ratio)?
Do you have any comments on or explanations of your answers to questions 17 – 19?
What do the authors say about the bias you chose in question 15?
What were the results of the study?
List the strengths of the study.
List the weaknesses of the study.
Do you agree with the authors’ conclusions?
