You are a member of a drug discovery team and tasked with identifying three potential targets for novel antibiotics. As you learned in BCH311, an ideal antibiotic will target prokaryotes but not eukaryotes.
Therefore, your team wants to engineer novel antibiotics that target prokaryotic information transfer (nucleotide biosynthesis, replication, transcription or translation) that will not affect humans. Your role on the team is the following:
A) Identify three differences between prokaryotes and eukaryotes regarding information transfer that could serve as a druggable targets.
Present this information to your team by designing a graphical abstract (1-page max) that illustrates these three differences. Include the three theoretical drugs in your figure, one for each of the differences you have highlighted, and clearly show where it would target. (6 marks)
B) Provide a figure caption to accompany your figure (350 words max) that explains the differences and highlights how your theoretical drugs would work. (4 marks)
