Question 1: (500 words)
What do you understand by the term ‘heterocyclic compound’?
Question 2: (500 words)
Clearly distinguish between the following compounds,
i) pyrrole
ii) furan
iii) thiophene
iv) Imidazole
Question 3: (500 words)
Discuss and critically evaluate the theory and applications of the following protein assays
-A280nm
-Coomassie
-Lowry
-BCA
Question 4: (300 words)
You are required to quantify a protein isolated from a downstream process. Discuss the method you would choose and why?
Question 5: (500 words)
Your company are introducing manufacture of a new small molecule API. Outline 2 analytical techniques you would choose to monitor the process. Include the background theory of the techniques and indicate at what stage of the process you would carry each out.
Question 6: (300 words)
Briefly outline the synthetic strategies available for production of single enantiomer drug products
Question 7: (500 words)
Discuss the importance of catalysis in API manufacture. Include information on the types of catalysts and give relevant API examples in your answer
Question 8: (300 words)
Explain the difference between an immunoassay and a bioassay, giving an example of one of each in detail.
Question 9:
Review techniques used in the purification of proteins (500 words)
